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Immune privileged site because of avascularity of the region. It is important to note that deep sub-tenon region (spaceīetween the sclera and the conjunctiva) acts as both natural culture medium for cells and as (subretinal, intravitreal, suprachoroidal and sub-tenon) have been employed to administer Multiple routes including systemic (intravenous) and localized Paracrine and immunomodulatory factors that are similar to those synthesized by retinal Umbilical cord derived mesenchymal stem cells (UMSCs) have the ability to release various Therapies have shown great promise for the management of RP. There is no definitive cure for patients suffering from RP. The disease initially starts with nightīlindness and leads to the loss of central vision and eventually total blindness. Retinal pigment epithelium and photoreceptors. Genetic mutation in any of these genes causes retinal degeneration by progressive loss of Various growth factors and their receptors are present in retinalĮpithelium and a number of genes are responsible for the production of these growth factors. Rods and cones largely depend on the retinal pigment epithelium for their Retinitis pigmentosa (RP) is the most common hereditary retinal disorder (accounts for 20% ofĬhildren attending blind schools in Pakistan) which causes degeneration of rod and cone Patients Per Site Per Month Study Details Study Description Brief Summary